ncRNA name | hsa-miR-101 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples, normal retinas; RB cell lines Y79 and WERI-RB1 |
Methods | qRT-PCR, transfection, luciferase reporter assay, MTT assay, colony formation assay, flow cytometry |
Expression pattern | down-regulated |
Functional description | Downregulation of miR-101 is associated with tumor aggressiveness in retinoblastoma and inhibits cell growth and proliferation of retinoblastoma cells by targeting EZH2. |
PubMed ID | 24807198 |
Year | 2014 |
Title | MiR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2. |
Drug-related ncRNA | NO |
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